Top CMOs in APAC
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Top 10 CMOs in APAC - 2020

With the increasing demand for generic medicines and biologics, the complex manufacturing requirements, and the capital-intensive nature of the business, many pharmaceutical companies have recognized the potential profitability in getting into agreement with a CMO for both clinical as well as commercial stage manufacturing. In addition, pharmaceutical companies have been directing their priorities toward the core areas of competency, and therefore, prefer not to dispense available resources, expertise, and technology on formulating the final dose of medicines.

Keeping at par with the paradigm shift in the biotechnology industry and the existing biopharmaceutical industry trends, CMOs have decided to shift from solely renting manufacturing units to a business model that offers extensive development and production support. CMOs and contract development and manufacturing organizations (CDMO) individually or together have begun to offer many specialized, value-added services for customers with early-stage development needs and for those who require support to generate a biologics license application enabling process validation data package.

CMOs have also started offering early development support to their customers, along with fully integrated services, which include specialized services like aseptic fill-finish. Though the concept of CDMO was introduced earlier, it has been fully realized over the last few years. It goes without saying that the costs invested in R&D are constantly increasing, and yet the useful results returned from these processes are becoming rarer. Many companies have realized that shifting this part of the business overseas and taking advantage of the still-emerging pharmaceutical markets is an effective method of cutting costs. Despite the existing proof of cost savings and competencies that can be accrued, many companies are reluctant to give up that control, going so far as to state that logistics are a core competency for the company. However, this scenario seems to be changing slowly.

The demand for API manufacturing has witnessed a sustained rise for some years, and it is expected to grow steadily and a subsequent increase in global generic production capacities. Most of the companies in the industry are overwhelmingly focusing on the development of biological APIs, which is driving the API market. The general prescription drug sub-segment occupies a major share in the API manufacturing segment, as compared to OTC drugs. Captive manufacturers are presently leading the API market, although they are expected to leave out their market share to contract manufacturers toward the end of the forecast period. This is entirely because of the complex and expensive in-house manufacturing of API and increasing competition from emerging players in the industry.

Our goal with this edition is to feature such companies who are at the forefront of revolutionizing the contract manufacturing organization space through their top-notch services. We hope this issue of the Pharma Tech Outlook helps you build the partnership you and your firm need to foster technologically-driven contract manufacturing organization services.

We present to you ‘Top 10 CMOs in APAC - 2020.’

Top CMOs in APAC

Bushu Pharmaceuticals is one of the best strategic partners for customers in the pharmaceutical industry, providingservices that range from the early development stage to the commercial production of pharmaceuticals. Bushu Pharmaceuticals started as a contract manufacturing organization for pharmaceuticals and clinical samples in 1999. Now, it provides solid support to companies with its wealth of experiences. As a global CDMO, the Bushu Pharmaceuticals Group becomes the customers’ partner, and helps them realize all their strategies and plans with the world-class technologies in its commitment to better human health with its value proposition.

www.bushu-seiyaku.co.jp

An Indonesia-based CDMO specialized in pharma products, cosmetics and traditional medicines, lab and clinical testing. Being a micro-enterprise of the Derma Global Ventura (DGV) group and a part of the Arya Noble Group Company, Genero has a comprehensive understanding of the various facets related to dermatology. This extensive industry know-how has been helping the company provide leading-edge skin solutions for the last 20 years. Today, Genero is conquering the entire SEA market with its semi-solid and liquid skin formulations. Besides contract manufacturing services, Genero also provides several other services and solution to its clients. These services include product formulation, analytical method and packaging development, product stability testing, pilot scale and process validation, product registration until commercial production, and sharing of R&D, QC lab and production facilities, among others.

genero.co.id

An Indian CDMO that offers development services starting from preclinical and going up to commercial manufacturing of early-stage intermediates, key starting materials, intermediates, and APIs. The company today has emerged as a reliable partner of the global life sciences industry as a manufacturer and supplier of active ingredients, intermediates, and biocides. Hikal specializes in scaling up enzymatic processes and is now investing in setting up a lab for demonstrating continuous manufacturing for its customers. To this end, Hikal applies a broad toolbox of chemical reactions at the industrial scale, such as energetic chemistry, chiral chemistry, biocatalysis. The company, moreover, has invested in solid-state chemistry using innovative analytical and manufacturing technology

www.hikal.com

A dedicated CMO and CDMO that invests heavily in drug development R&D and takes a compliance-driven approach to develop customized general medicines based on the market needs

peili.com.tw

An 83-year old family-owned group of companies thathelps pharma companies develop efficient products through its expertise in R&D, production, marketing, and contract manufacturing of traditional Chinese medicine, over-the-counter medicines, and cosmetics.

www.wenken.com

Akiyama

Akiyama

Based out of Tokyo, Akiyama Jozai Co., Ltd is one of the best pharmaceuticals manufacturing services that focus on quality and service. Akiyama offers contract manufacturing of medical tablets to the industry’s demands by actively creating new and improved forms. The company delivers high quality products, and strives to further improve the production technology through research and development. Akiyama flexibly supports the commercialization of everything from the development stage to formulations and containers. In addition, as manufacturing of pharmaceuticals becomes more specialized, Akiyama’s contract manufacturing under close partnership, strengthens each specialty area and improve business efficiency making it the key to future drug manufacturing

Bora Pharmaceuticals

Bora Pharmaceuticals

Striving to deliver quality with flexibility, Bora Pharmaceuticals is a leader in manufacturing and selling generic, brand, and over-the-counter (OTC) drugs to clients around the world. The company covers the entire pharmaceutical supply chain from research and development to sales and distribution. Bora Pharmaceuticals primarily focuses on Contract development and manufacturing (CDMO), Consumer Healthcare & OTC, and Prescription Drugs. Bora excels in providing services including outsourced R&D and toll manufacturing for Taiwan domestic and global pharmaceutical companies around the world. The company’s USFDA, MHRA, and PIC/S certified facilities produce pharmaceuticals of the highest medical standard for distribution to over 17 countries worldwide

ChemPartner

ChemPartner

ChemPartner is a life science CRO/CDMO service provider with over 16 years of experience serving innovative pharmaceutical research with a global reach. Evolved from a chemistry service provider, the company offers full service drug discovery and development for both small and large molecules, supported by biology, pharmacology, DMPK, and exploratory toxicology. As a Contract Development and Manufacturing Organization (CDMO), ChemPartner provide one-stop services for overall process development and IND application support, with a quality system in compliance with ICH guidelines and the highest standards of the CFDA, FDA and EMA. ChemPartner is uniquely positioned to not only be a CRO, but to be a true pharmaceutical alliance partner providing intellectual contributions and exceptional technical expertise

STA Pharmaceutical

STA Pharmaceutical

STA Pharmaceutical Co., Ltd., a WuXi AppTec company (WuXi STA), provides pharmaceutical development and manufacturing capability and technology platform, serving the life science industry, with operations in China and the United States. As a premier Contract Development and Manufacturing Organization (CDMO), STA Pharmaceutical offers efficient, flexible and high-quality solutions for small molecule Active Pharmaceutical Ingredients (APIs) and finished dosage forms from preclinical to commercial. With expertise in developing low soluble drugs and pediatric formulations, STA Pharmaceutical offers services and solutions for Drug Substance, Drug Product Development & Manufacturing, Oligonucleotide Service, Peptide Service, Analytical Development and Quality Control, and Global Regulatory Affairs CMC Filing

Vitex Pharmaceuticals

Vitex Pharmaceuticals

Vitex Pharmaceuticals, an Australian-owned and family operated company, is one the leaders in high-quality manufacturing of complementary pharmaceutical medicines. As a contract manufacturer of complementary medicine, Vitex Pharmaceuticals offer comprehensive and innovative solutions for leading brands and private labels including concept development, regulatory compliance, quality assurance, manufacturing, packaging and distribution. Vitex Pharmaceuticals specializes in the production of tablets, powders, soft gel capsules, extensive packaging solutions, and hard gel capsules among other related services. The company offers quality products and is committed to being the thought-leader of the industry, providing from the best-in-class manufacturing technology to outstanding services